The SPE (Secure Password Extension) gets its URL from PMAdmin -> General Settings -> Realm Instances.
If redirects or ssl/https connections are used, then the URL in the PMAdmin site also needs to be changed as it is not automatically updated with changes in IIS. The default is simply http:\\<servername>\PMUser.
This URL is published using a scheduled task that runs every 15 - 20 minutes. You can change the URL, then restart the PWM services.
Creating re-directs is outside the scope of support. See the following: https://support.quest.com/password-manager/kb/50225
for further details.