Selecting sites in the ISAPI agent configuration, but the changes are not being saved.
Also, the "Protected Sites" tab may be completely blank.
The account you are logged in with has insufficient permissions.
Verify that the account you're using is a member of the local administrators group on the system where IIS is running.
You may also try logging in with the local administrator account to confirm sites can be viewed and saved.
Alternatel, use the "Run As Administrator" option to start IIS and bypass any UAC (User Account Control) restrictions.