Bitlocker enabled on Windows Server 2012 /2019 and PCs are running Windows 10 Enterprise.
解决办法
There is no none issues with Defender Desktop Login (DSS) application forcing 2FA authentication on a machine that has Bitlocker installed on it. Also, none of the Defender services including DSS will interact or affect Bitlocker installed. Recommended to suggest testing this configuration in the test environment.